We Know: All About Acetyl-l-Cysteine

What Is Acetyl-l-Cysteine?

Acetyl-l-cysteine (also called acetylcysteine, n-acetyl-l-cysteine, NAC, and N-acetylcysteine) is derived from the amino acid cysteine and metabolizes into the antioxidant glutathione. Cysteines are especially valuable in stabilizing proteins intramolecularly. Insulin is an example of a stable structure provided by a cysteine, and the way cysteines bond proteins in hair determines whether your hair is curly, wavy, or straight.

Though you can take glutathione supplements to get that antioxidant, it's just as good and more cost effective to take acetylcysteine.


What Can I Use Acetyl-L-Cysteine For?

Acetyl-l-cysteine is used to treat a variety of physical issues, including in the following methods.

  • Cough medicine: it breaks up bonds in mucus to liquefy it so you can cough it up. It may also be delivered as an inhaled mist in some prescription medications for chronic respiratory conditions.
  • Treating oxidative stress in HIV, cancer, heart disease, and smoking.
  • Liver and kidney toxicity prevention.
  • Temporary loss of glutathione due to bodybuilding.
  • Treatment of acetaminophen overdose by preventing glutathione stores (which causes most of the damage).
  • Treatment of cocaine addiction and removal of mercury from the body (though these uses are debated currently).
  • Taken in conjunction with vitamin C and B1, it may be a good hangover preventative and treatment, though this has not been fully studied.

It is also possible that acetyl-l-cysteine, by stabilizing proteins, may someday help us unlock the secrets of Alzheimer's, Creutzfeldt-Jakobs, many rare blood diseases, and other diseases that are caused in part by incorrect folding of proteins resulting in amyloid accumulation.


Where Can I Get Acetyl-L-Cysteine And Other Cysteines?

One of the most common sources is from nutritional supplements, either with pure acetyl-l-cysteine or with a blend. You can also get it from the following foods:

  1. Red peppers, garlic, and onions
  2. Broccoli and brussels sprouts
  3. Oats and wheat germ


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